Noninvasive diagnosis of intraamniotic infection: proteomic biomarkers in vaginal fluid
نویسندگان
چکیده
منابع مشابه
Mass spectrometric detection of biomarkers for early assessment of intraamniotic fluid infection.
This data article contains information on glutathione sulfonamide (GSA) structural confirmation and purity after synthesis, as well as mass spectrometry acquisition parameters for the determination of GSA and other biomarkers for the early assessment of intraamniotic fluid infection in amniotic fluid samples (Cháfer-Pericás et al., 2015) [1]. GSA standards were synthesized and structural confir...
متن کاملDiagnosis of Vaginal Infection in Pregnancy
Pregnant women are prone to vaginal infection. At Primary Health Care Clinics diagnosis of causative organism of vagincll infections is made by clsing historp-taking and assessment of clinicalpicture methods. The accuracy of these methods is investigated in this stctdy by comparing the results obtained by historytaking and assessment of clinical picture with that which is obtained by examining ...
متن کاملApplicabillity of noninvasive biomarkers in prostate cancer diagnosis.
Prostate cancer represents the second leading cause of male cancer-related deaths worldwide. Better indicators of the presence of prostate cancer are needed to avoid unnecessary treatment, predict disease course and develop more effective therapy. Many molecular biomarkers have been described in human serum, urine, seminal fluid and histological specimens that exhibit varying capacities to dete...
متن کاملDiagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers.
CONTEXT Intra-amniotic infection (IAI) is commonly associated with preterm birth and adverse neonatal sequelae. Early diagnosis of IAI, however, has been hindered by insensitive or nonspecific tests. OBJECTIVE To identify unique protein signatures in rhesus monkeys with experimental IAI, a proteomics-based analysis of amniotic fluid was used to develop diagnostic biomarkers for subclinical IA...
متن کاملSoluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection.
TLRs are pattern recognition transmembrane receptors that play key roles in innate immunity. A recently discovered soluble truncated form of TLR2 (sTLR2) acts as a decoy receptor, down-regulating the host inflammatory response to bacteria. To identify the presence and functional role of sTLR2 in modulating the intraamniotic inflammatory response to infection, we studied 109 amniotic fluid sampl...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2010
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2010.03.037